Yuwen Chen

Hock, Duke University

2080 Duke University Road

Durham, NC 27708

I am currently a 4th-year ECE PhD student at Duke University focusing on AI + healthcare. I am fortunate to be advised by Prof. Maciej A. Mazurowski. I have worked at Siemens Healthineers as a Research Scientist Intern.

My research interests primarily lie in foundation models, vision-language models, agentic systems, generative models, learning under data distribution shifts, and advancing AI solutions for real-world challenges.

Prior to my Ph.D., I earned master’s degrees in Electrical and Computer Engineering from Carnegie Mellon University, where I was advised by Prof. Zachary Lipton, and from Imperial College London, where I was supervised by Prof. Jesus Rodriguez Manzano. I completed my undergraduate studies through the 2+2 program at the University of Nottingham, where I primarily worked with Dr. David Siu Yeung Cho.

See my Google Scholar for a full list of my publications, with a few recent highlights shown below.

news

Nov 02, 2025	🔥 Our paper on unpaired image translation using contour-guided diffusion model (ContourDiff) has been accepted for publication in Machine Learning for Biomedical Imaging (MELBA).
Oct 28, 2025	🔥 Our paper on accelerating volumetric medical image annotation (SLM-SAM 2) has been accepted for publication in IEEE Transaction on Medical Imaging (IEEE TMI).
Apr 15, 2025	🔥 Our paper on universal bone segmentation is accepted by Medical Image Analysis.
Jun 15, 2024	🔥 Our paper on anatomically-controllable image generation is accepted by MICCAI.

selected publications

IEEE TMI

Accelerating Volumetric Medical Image Annotation via Short-Long Memory SAM 2

Yuwen Chen, Zafer Yildiz, Qihang Li, and 5 more authors

IEEE Transactions on Medical Imaging, 2025

DOI Bib HTML

@article{chen2025accelerating,
  title = {Accelerating Volumetric Medical Image Annotation via Short-Long Memory SAM 2},
  author = {Chen, Yuwen and Yildiz, Zafer and Li, Qihang and Chen, Yaqian and Dong, Haoyu and Gu, Hanxue and Konz, Nicholas and Mazurowski, Maciej A},
  journal = {IEEE Transactions on Medical Imaging},
  year = {2025},
  doi = {10.1109/TMI.2025.3627954},
}

MELBA

ContourDiff: Unpaired Medical Image Translation with Structural Consistency

Yuwen Chen, Nicholas Konz, Hanxue Gu, and 5 more authors

Machine Learning for Biomedical Imaging, 2025

DOI Bib HTML

@article{chen2025contourdiff,
  title = {ContourDiff: Unpaired Medical Image Translation with Structural Consistency},
  author = {Chen, Yuwen and Konz, Nicholas and Gu, Hanxue and Dong, Haoyu and Chen, Yaqian and Li, Lin and Lee, Jisoo and Mazurowski, Maciej A},
  journal = {Machine Learning for Biomedical Imaging},
  volume = {3},
  pages = {711--727},
  year = {2025},
  doi = {10.59275/j.melba.2025-79a2},
}